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Bioinformatic Data and Pathway Analysis

Cellecta has partnered with Ariadne to offer a comprehensive Pathway Analysis service for downstream analysis of all of your high-throughput siRNA library functional analysis data. The computational validation of positive siRNA clones aims to find plausible signaling mechanisms connecting the effect of inhibition of siRNA target protein and observed phenotype. We will use the searches against the comprehensive database of pathways and protein interactions to report:

  • The lists of pathways affected by each of the identified siRNA clones.
  • The common pathways, downstream events or upstream regulators for the sets of siRNAs.
  • Expression profiles for corresponding genes as available from the public datasets.
  • Similar biological effects of siRNA targets or other functionally related genes if known in the literature.

Pathway Studio software screen capture showing complex diagram of pathway
Pathway Studio® pathway analysis software: build pathways and visualize them in color and according to cellular localization.

As an option, the analysis results can be delivered in a format compatible with the software package Pathway Studio® to enable additional analysis of pathways involved and integration with the prior knowledge and profiling data.

Scientists with background and experience second-to-none make Cellecta a leader in the functional genomics service industry. By offering a complete package of functional analysis services, we can now be your single source to quickly get you and your lab from phenotype to gene to pathway to publication.