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Cellecta Scribe™ Vectors Enable RNA-Seq Analysis of Pooled CRISPR and RNAi Screens

Earlier this year, 3 separate studies (Adamson, et al., Datlinger, et al., and Dixit, et al.) demonstrated an approach to combine pooled CRISPR genetic screening with RNA expression profiling at the single-cell level. Integrating these two approaches enables...

A New GFP CRISPR for Primary and Non-Dividing Cells

Use of antibiotic resistance markers with CRISPR is an effective tool for cells that proliferate.  However, for primary cells and non-dividing cells, all-in-one sgRNA-Cas9 lentiviral vector that contains a fluorescence marker (GFP-CRISPR) could be a better option. Our...