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Cellecta Blog & News

We have started the Cellecta blog as a simple, unobtrusive conduit that enables us to talk directly to our customers, collaborators, and other interested researchers about new and interesting developments related to Cellecta’s technology and business. Check back here often for the latest news and events.

About Cellecta

Cellecta Inc., a custom and contract functional genomics solutions provider, focuses primarily on developing and implementing flexible and scalable broad-based screening and analysis approaches for drug target and biomarker discovery. Our high throughput functional genetic screening portfolio includes shRNA and CRISPR screening services, custom and off-the-shelf pooled libraries, and knockout/knockdown cell lines that facilitate genome-wide functional screening and the identification and validation of genes involved in critical biological and pathological responses.

With our new DriverMap™ Gene Expression and Molecular Profiling Service, Cellecta now offers a quantitative, multiplexed approach that allows simultaneous profiling of thousands of genes in one reaction, thereby providing the transcriptome profile of the tumor microenvironment.

A New GFP CRISPR for Primary and Non-Dividing Cells

Use of antibiotic resistance markers with CRISPR is an effective tool for cells that proliferate.  However, for primary cells and non-dividing cells, all-in-one sgRNA-Cas9 lentiviral vector that contains a fluorescence marker (GFP-CRISPR) could be a better option. Our...

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German Researchers Find Sensitizer for Gemcitabine Using DECIPHER RNAi Libraries

Researchers at the German Cancer Research Center (DKFZ) used Cellecta's shRNA DECIPHER libraries to identify genes that sensitize pancreatic cells to gemcitabine. Pancreatic cancer has only a 6% 5-year survival rate. Gemcitabine is the standard treatment in...

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Second Phase SBIR Contract from the National Cancer Institute (NCI) to Identify Lethal Gene Combinations in Cancer Cell Models

It's been a while since the last post to this blog. It is not that nothing has been going on, in fact, quite the opposite. It has been quite busy the past several months and, unfortunately, blog postings have suffered. However, I thought I would get things started...

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