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CRISPR Products

The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and CRISPR-associated (Cas) genes denoted as the CRISPR/Cas9 system is a targeted gene-editing tool adapted from Streptococcus pygogenes that can be used to permanently knock out target genes. Guide RNAs (sgRNA or gRNA) direct the Cas9 nuclease to a specific genomic region upon which Cas9 cleaves the target gene, permanently knocking it out.

Cellecta has developed effective, time-saving tools for functional gene analysis using CRISPR technology.

Convenient online ordering of all off-the-shelf CRISPR products including libraries, kits, constructs, and vectors is now available. Specific instructions for custom orders are available on the Order page.

 

CRISPR Library BooksCellecta’s CRISPR Human Genome Knockout Libraries provide ready-to-use, lentiviral-based, pooled sgRNA libraries that target all of the nearly 20,000 protein-encoding genes in the human genome.

Single-Module CRISPR Human Genome-Wide 80K Knockout Library and original Three-Module CRISPR Human Genome-Wide 150K Knockout Library

New! Human CRISPRa and CRISPRi and Mouse CRISPRa and CRISPRi Genome-Wide Libraries

New! Single-Module CRISPR Mouse Genome-Wide 80K Knockout Library

CRISPRtest CRISPR Functional Cas9 Activity Kit FACS scatter plotCRISPR-Test Cas9 Assay Kits enable accurate assessment of Cas9 activity in human and other mammalian cells.

Next-generation sequencing (NGS) analysis kits to obtain read counts from screens of your library of choice are also available.

Custom CRISPR Knockout ConstructsWe also offer several lentiviral Cas9 Expression Plasmids that can  be used to make Cas9+ cells for CRISPR screens, or targeted gene knockout experiments. In addition, to support these application,s we offer a panel of CRISPR control constructs and sgRNA Cloning Vectors