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Mouse Genome-Wide CRISPR Knockout Library

Cellecta’s Mouse Genome-Wide CRISPR Knockout Library was designed to be small enough to enable convenient, genome-wide “dropout viability” screens. With less than 80,000 constructs, the mouse CRISPR library targets all mouse protein-coding genes (~19,600) with 4 sgRNAs/gene. It is designed to target functional domains and regions conserved between alternatively spliced transcripts.

Genome-Wide Coverage with a Single 80K Module

  • Single library with ~80,000 constructs
  • Each gene is covered by 4 sgRNAs designed to target functional domains and conserved transcript regions
  • All mouse protein-coding genes covered—approximately 19,600 gene targets

Complete Panel of Controls

  • Standard non-targeting controls
  • Controls for non-specific cutting (sgRNA targeting introns throughout the genome)
  • Lethal sgRNA targeting generally essential genes (i.e., positive controls for dropout screens)

If you are interested in a custom library, Cellecta can help. Visit our Order page for specific instructions.

 

Ordering information

NOTE: Cellecta offers academic discounts on many of our pre-packaged libraries to qualifying academic institutions. Please email orders@cellecta.com using your institutional email account, to ask for a quote with the discounted pricing.

Catalog#NameCategoryPriceBuy
KOMGW-80K-PCRISPR Mouse Genome 80K Knockout Library, (plasmid)$10,000.00
10000
KOMGW-80K-V9CRISPR Mouse Genome 80K Knockout Library, (virus)$18,000.00
18000
KOMGW-80K-V8CRISPR Mouse Genome 80K Knockout Library, (virus)$8,500.00
8500

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