Genetic Profiling and Functional Screening for Drug Target and Biomarker Discovery
Join us for a workshop on Tuesday, April 2 from 3:00 to 4:00 pm, Spotlight Theatre C, AACR Exhibit Hall, Georgia World Congress Center, Atlanta, GA
Stop by and see us at Booth 4218.
- new functional genomics technologies to understand complex diseases
- novel way to combine genetically engineered mouse models of cancer with DNA barcoding to gain insight into carcinogenesis
Efficient tools to enable drug target and biomarker discovery: a brief introduction to Cellecta technologies
Paul Diehl, Ph.D., COO, Cellecta, Inc.
Quantitative and multiplexed in vivo functional cancer genomics using barcoded CRISPR libraries
Ian P. Winters, Ph.D., Director of Research, D2G Oncology
Large-scale sequencing of human tumors has uncovered a vast array of genomic alterations. Genetically engineered mouse models recapitulate many features of human cancer and have been instrumental in assigning biological meaning to specific cancer-associated alterations. However, their time, cost- and labor-intensive nature limits their broad utility; thus, the functional importance of the majority of genomic aberrations in cancer remains unknown. Here, we combine genetically engineered mouse models of cancer with CRISPR-mediated genome editing, DNA barcoding, and next-generation sequencing to simultaneously investigate the function of many genomic alterations in vivo and uncover novel biological and clinically actionable insights into carcinogenesis.
Thank you for your interest in Cellecta technologies. We look forward to seeing you at the 2019 AACR Annual Meeting
Where: Spotlight Theatre C, AACR Exhibit Hall
When: Tuesday, April 2, 2019, 3:00 to 4:00 pm
Feel free to forward this invitation to your interested colleagues.
For more information on Cellecta, stop by and see us at AACR Booth 4218.
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