For targeted gene knockouts and screening using CRISPR, CRISPRa, or CRISPRi, Cellecta offers lentiviral plasmids that express S. pyogenes Cas9 nuclease or dCas9 (dead-Cas9). The constructs are available in both packaged and plasmid forms.
For use with CRISPR gene inhibition (CRISPRi) or gene activation (CRISPRa) systems, plasmids expressing either dCas9-KRAB or dCas9-VPH are available.
We can also provide other configurations of Cas9 or dCas9 expression plasmids on a custom basis. Please inquire if you require something different than the items described above.